Plain-English translation of NCT04858009 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a treatment called (HIPEC) for people with pancreatic cancer that has spread to the tissue lining the abdomen. The treatment uses heated chemotherapy drugs— and —delivered directly into the abdomen during surgery, allowing the medication to work directly on cancer cells in that area. Researchers want to see whether this medication can help people with this advanced type of cancer live longer and stay cancer-free.
Pancreatic cancer that spreads to the abdominal lining is very difficult to treat with standard chemotherapy alone. This trial exists to test whether delivering heated chemotherapy directly to the affected area—rather than through the bloodstream—might be more effective and help improve survival for patients in this situation.
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If you join this trial, you will undergo a surgical procedure in which the heated chemotherapy treatment is delivered directly into your abdomen over 90 minutes. You may receive up to 5 additional treatments depending on how well you tolerate the medication and how your cancer responds. Throughout the trial, you will have imaging scans (CT, MRI, or PET) to monitor your progress, and after your treatment ends, you will be followed up with visits every 6 months to track your health and survival.
AI-generated summary from trial data · Jun 27, 2026 · Not medical advice
United States