Plain-English translation of NCT04859088 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Crohn Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a simple dietary change — replacing half your normal food with specially designed nutritional shakes — can boost the effectiveness of adalimumab, an injectable medication that reduces inflammation in Crohn's disease. You would receive the medication as part of your standard care, and half of participants will also drink these shakes for 6 weeks while the other half eat normally. The study will track whether the combination helps more people achieve remission (symptom-free periods) and stay well longer.
While this medication works well for many people with Crohn's disease, doctors want to know if adding a specific nutrition strategy could help it work even better and help more patients reach remission faster and stay symptom-free longer.
You likely qualify if…
You likely don't qualify if…
You would receive your standard adalimumab injections as normal. Then you would be randomly assigned to either drink the special nutritional shakes (replacing half your daily calories for 6 weeks) or continue eating your regular diet. The study team would check in with you at 6 weeks and 12 weeks to see how you're feeling, measure your disease markers with blood tests, and follow your progress for up to a year to see if your symptoms stay away.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
United Kingdom