Plain-English translation of NCT04862663 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This study is testing whether —a new medication—works better when combined with two standard breast cancer drugs (a CDK4/6 inhibitor and ) compared to the two standard drugs alone. The trial involves nearly 900 people with advanced breast cancer that relies on hormones to grow and hasn't responded to or has returned after earlier hormone treatments.
Current treatments with two drugs help many patients, but some still see their cancer grow or return. This medication is being tested to see if adding it to the standard treatment can help more patients live longer and keep their cancer under control.
You will receive treatment either with the new three-drug combination or with the two standard drugs alone (decided randomly). You'll visit the clinic regularly for check-ups, blood tests, and scans to see how the treatment is working and monitor for side effects. The trial has two phases: an initial phase to find the right doses, followed by a larger phase that will determine if the new combination is more effective than standard treatment.
AI-generated summary from trial data · Aug 27, 2026 · Not medical advice
United States