Plain-English translation of NCT04864886 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand how immune system cells use energy differently in people with conditions like psoriasis, atopic dermatitis, and primary immunodeficiency compared to healthy people. By studying blood, skin, and other samples, the team hopes to identify unique patterns that could lead to better treatments in the future.
Currently, doctors don't fully understand how the immune system behaves at a metabolic level in these diseases. This knowledge gap makes it harder to develop targeted treatments, so researchers are collecting detailed samples to map out these differences.
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If you can visit the research site, you'll have blood drawn and may undergo up to four small skin biopsies over several weeks to capture how your skin heals. Some participants may also have a blister induction procedure on their forearm to collect skin cells. If you cannot visit in person, you can participate by completing surveys and optional at-home sample collection. The entire study takes several weeks to complete.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States
Enrollment target
~300 participants
Started
August 2021
Primary completion
June 2027
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jodi L Blake, R.N.
National Institute of Allergy and Infectious Diseases (NIAID)
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.