Plain-English translation of NCT04864886 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand how the body's chemistry changes when the immune system isn't working properly. This study collects blood, skin biopsies, and other samples from people with conditions like atopic dermatitis, psoriasis, or primary immunodeficiency — as well as from healthy people — to map out these chemical changes and learn what makes immune-mediated diseases develop.
Scientists believe that immune system problems involve changes in how cells use energy and produce chemicals. By collecting and studying these samples, researchers hope to discover new ways to diagnose and treat immune-mediated diseases more effectively.
You likely qualify if…
You likely don't qualify if…
If you can visit the clinic, you'll have an initial blood draw and screening visit, followed by skin biopsies (small samples removed with a punch tool). You may return 3–14 days later for additional biopsies to see how your skin heals. The study may also include optional blister induction on your forearm, skin swabs, tape strips, and urine collection. If you cannot attend in-person visits, you can participate remotely by completing surveys and mailing in optional home samples. The entire study takes about 2–3 weeks from start to finish.
AI-generated summary from trial data · Sep 2, 2026 · Not medical advice
United States