Plain-English translation of NCT04871399 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a newer surgical technique called Complete Mesocolic Excision with Central Vascular Ligation (CME+CVL) works better than standard surgery for patients with right-sided colon cancer. In CME+CVL, surgeons remove the cancer along with more of the surrounding tissue and blood vessels in a very careful, controlled way. The study will follow patients for five years after surgery to see if this approach helps them live longer without their cancer returning.
Standard surgery for right colon cancer has been used for many years, but some surgeons believe that removing more of the surrounding tissue and blood vessels — as done in CME+CVL — could improve survival rates and reduce the chance of cancer coming back. This trial aims to find out if this newer, more detailed surgical approach truly offers better results than the conventional method.
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If you join this study, you will be randomly assigned to receive either the newer CME+CVL surgery or standard colon cancer surgery. Your surgeon may perform the operation using open surgery, laparoscopy (small incisions with a camera), or robotic assistance — whichever is best for you. After surgery, you will have follow-up appointments at 1 month, 4 months, 1 year, 2 years, 3 years, and 5 years to check your health and monitor for any signs of cancer returning. The entire study will take about 6.5 years from start to finish.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
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