Plain-English translation of NCT04875364 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial investigates why some people develop obstructive sleep apnea and how the underlying cause affects which treatment works best for each person. Researchers will test how three different approaches — a CPAP machine, the medication , and supplemental oxygen — affect your symptoms and blood pressure. By understanding what drives your sleep apnea, doctors hope to personalize treatment and prevent serious complications.
Currently, doctors treat all sleep apnea patients similarly, but people respond very differently to the same treatment. This study exists to understand the root causes of sleep apnea in different people so that doctors can match each patient with the treatment most likely to help them.
You likely qualify if…
You likely don't qualify if…
You will come in for several overnight sleep studies in a lab. First, researchers will establish your baseline sleep apnea severity with two initial studies. Then you'll participate in two experimental nights where you'll try or supplemental oxygen in random order to see how each affects your sleep. After that, you'll either receive a loaner CPAP machine right away or wait about 8 weeks while receiving standard clinical care. Throughout, researchers will track your daytime sleepiness, blood pressure, and how well you tolerate each approach.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
United States