Plain-English translation of NCT04881487 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether stereotactic body radiation therapy (SBRT)—a type of focused, high-dose radiation delivered very precisely to a small area—can help people whose pancreatic cancer has returned in one spot after surgery. Some people in the trial will receive SBRT along with their regular chemotherapy and care, while others will receive chemotherapy and care alone. The goal is to see if adding this radiation treatment helps people live longer and feel better.
Pancreatic cancer often comes back after surgery, and when it does, it usually comes back in the area where the cancer started. Right now, doctors mainly treat recurrence with chemotherapy, but the cancer can cause serious pain and problems in that local area. Recent research suggests that focused radiation therapy might help control the cancer in that specific spot better, which could improve survival and quality of life.
You likely qualify if…
You likely don't qualify if…
If you join this trial, you will be randomly assigned to one of two groups: one group will receive focused radiation therapy (SBRT) in addition to their regular chemotherapy and supportive care, while the other group will receive chemotherapy and supportive care alone. You will have imaging scans to plan your treatment, and if you are in the radiation group, you will receive several sessions of focused radiation over a few weeks. Throughout the trial, your doctors will monitor how well you are doing, check your survival, and ask about your quality of life.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
Netherlands