Testing heart imaging to evaluate blocked arteries in severe valve disease

This trial is investigating the best way to detect and evaluate blocked arteries in people who have severe aortic valve disease (a condition where the heart valve doesn't open properly). Researchers will use three different heart imaging methods—two called FFR and iFR, and one called PET perfusion imaging—to see which ones work best together to identify blockages that need treatment.

When patients have severe aortic valve disease, their hearts work harder and their blood vessels behave differently than in people without this condition. This means that the standard tests doctors use to detect blocked arteries may not work as well, potentially leading to patients not getting the treatment they need. This study aims to find out which imaging methods are most reliable in this specific patient population.