Plain-English translation of NCT04883515 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether oral glutamine supplementation—a simple amino acid you take by mouth—can help improve blood sugar control and digestive problems in people living with obesity. The researchers believe that glutamine may help repair your gut lining, which could lead to better blood sugar management and fewer digestive symptoms. Half the participants will receive glutamine, and half will receive a protein powder placebo, so researchers can compare how well the treatment works.
Many people with obesity struggle with both high blood sugar levels and irritable bowel symptoms, which can seriously affect quality of life. Recent research suggests that the gut lining plays an important role in these problems, and glutamine may help restore that lining—but this hasn't been thoroughly tested in people yet.
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You will take either glutamine or a protein powder supplement three times a day for 8 weeks. During the study, you'll have blood tests and provide stool samples at the start, after 8 weeks, and again 8 weeks after you stop taking the supplement. The researchers will also measure how well your gut barrier is working using special tests, so they can track whether the treatment is helping.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
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