Plain-English translation of NCT04891029 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers at McGill University have developed a new screening test that looks for early genetic signs of ovarian and endometrial cancer in a simple uterine cell sample and a saliva sample. The test uses advanced computer analysis to spot cancer-related genetic changes that may appear long before a woman has any symptoms. This trial will test whether this new approach can catch these cancers much earlier than current methods.
Ovarian and endometrial cancers often have no warning signs until they've already advanced to a serious stage. Current screening tests don't work well for these cancers, so doctors need a better way to find them early when treatment is most effective.
You likely qualify if…
You likely don't qualify if…
If you join, you would provide a uterine cell sample (similar to a Pap test) and a saliva sample, which researchers would analyze using the new genetic test. The study will also look for inherited cancer risks in your saliva sample. The exact number of visits and timeline aren't fully detailed, but enrollment is ongoing for up to 5,600 women.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Canada
Sponsor
McGill University
Collaborators
Genome Canada, Genome Quebec
Enrollment target
~5,600 participants
Started
May 2021
Primary completion
November 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
45 Years – 75 Years
Sex
Female only
Last updated on clinicaltrials.gov in June 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Lucy Gilbert, MD
McGill University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.