Plain-English translation of NCT04906863 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers at Columbia University are studying the genes that may cause dementia and memory loss when they start at a younger age. By comparing genetic information from people with memory problems, their relatives, and healthy volunteers, scientists hope to find patterns that could help explain why some people develop these conditions earlier than others.
Early-onset dementia is not yet well understood, and there are few treatments available. By identifying the genes involved, researchers hope to develop better ways to diagnose, prevent, and eventually treat memory loss and dementia in younger people.
You likely qualify if…
You likely don't qualify if…
If you enroll, you will likely be asked to provide a blood sample for genetic testing and possibly answer questions about your medical and family history. The study compares genetic information from people with memory concerns, people with dementia, and healthy volunteers to find common patterns. The exact number and timing of visits will depend on your role in the study—whether you have memory concerns yourself or are participating as a healthy family member.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
United States
Collaborators
University of Miami, National Institute on Aging (NIA)
Enrollment target
~1,000 participants
Started
September 2016
Primary completion
April 2028
Age range
35 Years and older
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Pamela Del Rosario
Columbia University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.