Advanced MRI scans to guide radiation therapy for children with brain tumors

This trial is testing whether a special type of MRI scan called spectroscopic MRI (sMRI) can help doctors better plan and deliver radiation therapy for children with high-grade brain gliomas. The study has two main parts: first, doctors will collect baseline MRI information from patients before they receive standard radiation therapy to see if it predicts where tumors might come back; second, doctors will test whether this special MRI scan can safely be used to define the exact area that needs radiation treatment, potentially reducing radiation to healthy brain tissue.

Children with high-grade brain gliomas need radiation therapy, but doctors currently use standard MRI to plan treatment, which may not show the most active parts of the tumor. This trial exists to see whether a more detailed MRI technique can better identify tumor activity and help doctors design more precise, safer radiation plans that protect healthy brain tissue.