Plain-English translation of NCT04912518 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
This study doesn't follow the usual testing phases โ it may be an observational study or a different type of research.
This trial is testing whether a medication called dexmedetomidine can protect your heart during emergency treatment for a front-wall heart attack. The medication is given intravenously (through an IV) while you receive a catheter procedure to open your blocked artery. Researchers want to know if this treatment reduces the amount of heart damage compared to a placebo (a saline solution with no active medication).
Heart attacks cause permanent damage to heart muscle, and the amount of damage affects how well your heart works long-term. This medication is being tested because early research suggests it may reduce the size of heart damage during the emergency treatment procedure.
You likely qualify ifโฆ
You likely don't qualify ifโฆ
If you qualify and enroll, you will receive either dexmedetomidine or a saline placebo through an IV starting immediately and continuing throughout your emergency catheter procedure. The study team will monitor your heart rate and blood pressure and adjust the medication dose as needed. About 5โ7 days after your heart attack, you will have a heart imaging scan (cardiac MRI) to measure how much heart damage occurred. You will then be followed as part of standard heart attack care.
AI-generated summary from trial data ยท Aug 6, 2026 ยท Not medical advice
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