Testing an injection for severe facial and head pain relief

This trial is testing whether Exparel, a long-acting numbing medication, can help relieve severe facial and head pain when injected through an endoscope (a thin camera) into a specific area near the nasal cavity. The medication is already used successfully in surgery to provide pain relief for up to 72 hours, and researchers want to see if this treatment can help people with migraines, cluster headaches, and other types of severe facial pain.

Many people suffer from severe, hard-to-treat facial and head pain that doesn't respond well to regular treatments. This trial exists because early signs suggest that numbing a specific nerve pathway in the nasal area might provide significant pain relief, and researchers want to test whether this medication can safely and effectively help patients.