Plain-English translation of NCT04931160 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is a long-term research study that follows people with suspected Sjögren syndrome — an autoimmune condition where the body attacks moisture-producing glands, causing dry eyes and mouth. The study collects blood samples, health information, and imaging results over 10 years to help doctors understand how the disease develops and progresses.
Doctors still have a lot to learn about Sjögren syndrome, including why some people develop it and how to predict who will have the most severe symptoms. By following many patients over time and collecting their biological samples, researchers hope to identify new patterns and biomarkers that could lead to better diagnosis and treatment.
You likely qualify if…
You likely don't qualify if…
If you have suspected Sjögren syndrome, you'll have visits at the start of the study, then again at years 2, 3, 4, 6, 8, and 10 — your doctor will determine the exact schedule based on your situation. At some visits (the start, year 4, and year 10), you'll also donate blood, saliva, urine, and cell samples. Control participants without Sjögren syndrome will have just two visits (at the start and year 4) with samples collected at those same timepoints.
AI-generated summary from trial data · Jun 29, 2026 · Not medical advice
France
Sponsor
University Hospital, Brest
Enrollment target
~1,000 participants
Started
February 2020
Primary completion
February 2035
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Valérie Devauchelle, MD,PhD
CHRU BREST
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.