Healthy Gut Bacteria to Prevent Complications After Blood Stem Cell Transplant

This trial is testing whether Fecal Microbiota Transplantation (FMT)—a procedure that transfers healthy gut bacteria from donors into patients—can help prevent a serious complication called graft-versus-host disease after stem cell transplant for blood cancers. After a stem cell transplant, your gut bacteria are often destroyed by the treatment, which can lead to problems with infection and inflammation. The study compares patients who receive this treatment against those who don't, to see if restoring healthy bacteria helps you recover better.

Stem cell transplants save lives but often damage the healthy bacteria in your gut, which can lead to dangerous infections and a painful condition where the new immune cells attack your own body. Researchers believe that giving patients back healthy gut bacteria might prevent these complications and help them survive longer.