Plain-English translation of NCT04940962 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers are studying fat tissue to understand how natural chemicals in your body (called endocannabinoids) affect weight and blood sugar control. This study compares fat tissue from people without diabetes, people with obesity but no diabetes, and people with both obesity and type 2 diabetes. The goal is to learn whether blocking certain receptors that respond to these natural chemicals could help reduce their overproduction in fat tissue.
People with obesity and type 2 diabetes have overactive endocannabinoid systems, which may be making their conditions worse by increasing hunger and disrupting how their body handles sugar and fat. Scientists need to understand exactly how this happens in human fat tissue so they can develop better treatments.
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If you qualify, a small sample of your fat tissue will be collected during abdominal surgery you are already scheduled to have. The researchers will then study this tissue in the laboratory to measure natural chemicals and other substances. There are no additional visits or medications required — the study simply uses tissue that would otherwise be discarded during your surgery.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
France