Targeted radiation therapy for breast cancer that has spread to bones

This trial is testing fractionated stereotactic radiation therapy (FSRT)—a highly focused form of radiation that delivers strong doses to tumors in the bones while sparing surrounding healthy tissue. The treatment is being studied in people with breast cancer that has spread to their bones and who have not responded well to standard radiation or surgery, or who cannot have surgery. Researchers want to see if this targeted approach can control pain and tumor growth better than conventional treatments.

When breast cancer spreads to the bones, it can cause severe pain and weakening of bone strength. Standard radiation therapy helps some patients, but not all—and some patients cannot have surgery. This trial exists to find out whether this newer, more precise radiation technique can help patients whose cancer has not responded to earlier treatments.