Plain-English translation of NCT04947657 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Atrial Fibrillation research guide →This is a 3-month research study for people with atrial fibrillation who are having their first catheter ablation procedure — a minimally invasive treatment to restore normal heart rhythm. Researchers want to understand how certain blood markers (clotting-related proteins) change before, during, and after this procedure, and whether these markers can predict how well the ablation works long-term.
Atrial fibrillation causes irregular heartbeat and increases stroke risk. While catheter ablation is an effective treatment, doctors don't yet have good ways to predict which patients will have the best long-term results. This study hopes to identify blood markers that could help predict success and improve outcomes for future patients.
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You'll have blood drawn before your ablation procedure, twice during the procedure itself (once from a vein in your arm and once from inside the heart), and then again the day after ablation, at 1 month, and at 3 months. You'll also have a cardiac MRI scan before ablation, which is already standard care. Throughout the 3 months, researchers will collect some information from your medical records and may ask you to wear an FDA-approved heart monitoring patch. All your data will be stored securely and kept confidential.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
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