Plain-English translation of NCT04948749 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial compares two treatment approaches for people who've recently had a stroke caused by a narrowed artery inside the brain. One group receives a drug-eluting stent (a tiny mesh tube coated with sirolimus, a medication that prevents the artery from closing again) along with more aggressive blood-thinning medicines taken for a longer period. The other group receives standard blood-thinning medicines without the stent procedure.
People with narrowed blood vessels inside the brain face a high risk of having another stroke. Doctors want to know whether this medication-coated stent, combined with stronger and longer treatment with blood thinners, can reduce that risk more effectively than medicines alone.
You likely qualify if…
You likely don't qualify if…
If you are assigned to the stent group, you will undergo a procedure to place the drug-coated stent in your narrowed brain artery, followed by taking dual blood-thinning medications (two types of blood thinners together) for 6 months, then one blood thinner for the rest of the study. If you are assigned to the standard treatment group, you will take dual blood thinners for 3 months, then switch to one blood thinner. Both groups will also work on managing risk factors like blood pressure, diabetes, cholesterol, smoking, and exercise. You will have follow-up visits and imaging tests to monitor for any new strokes over the course of one year.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
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