Plain-English translation of NCT04949464 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
This study doesn't follow the usual testing phases โ it may be an observational study or a different type of research.
This study is testing whether a smartphone app called Positively Smoke Free - Mobile, combined with nicotine replacement therapy and lung cancer screening, can help people living with HIV quit smoking. Smoking is a major health risk for people with HIV, increasing the chance of lung cancer and other serious diseases. Researchers want to see if this combination approach works and whether people will actually use and stick with the smartphone app.
People living with HIV who smoke face higher risks of lung cancer and other smoking-related illnesses compared to people without HIV. There is a need for smoking cessation tools specifically designed for people with HIV, and researchers want to see if pairing behavioral support through a smartphone app with nicotine replacement and lung cancer screening can help more people successfully quit.
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You would use the Positively Smoke Free - Mobile app on your smartphone every day for 42 days and receive nicotine replacement therapy (like patches or gum) for 12 weeks to help manage cravings. Within 60 days of joining the study, you would have a low-dose CT scan of your lungs to screen for lung cancer. After that, you would have follow-up visits at 3, 6, and 12 months to check on your smoking status, how you're feeling, and whether the app and treatment helped you quit.
AI-generated summary from trial data ยท Jun 9, 2026 ยท Not medical advice
United States