Plain-English translation of NCT04965675 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This study is testing a medication called to see if it can help prevent chronic migraines in teenagers. works by blocking a protein in the body that's involved in migraine pain. You would receive a single intravenous infusion (through an IV) of either the medication at one of two doses or a placebo (a non-active treatment), and researchers would track your migraine patterns over several months to see if the treatment helps.
Chronic migraines in teenagers can seriously affect their school, social life, and overall well-being. Current prevention options are limited, so researchers are testing this medication to see if it offers a new, effective way to reduce how often teens experience migraines.
You likely qualify if…
You likely don't qualify if…
First, you'll enter a 4-week screening period where you'll keep a daily digital diary of your headaches to confirm you qualify. If you do, you'll receive a single intravenous infusion of either the medication or placebo at your randomization visit. Then you'll be in the main 12-week study period, during which researchers will track your migraine patterns. Finally, there's an 8-week safety follow-up period where the research team will check in to make sure you're doing well. The entire study lasts about 6 months.
AI-generated summary from trial data · Jul 15, 2026 · Not medical advice
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