Plain-English translation of NCT04967183 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Colorectal Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a simple yearly blood test (called a fecal immunochemical test, or FIT) works just as well as repeat colonoscopies to catch colorectal cancer early in people who have already had precancerous polyps removed. Right now, doctors routinely recommend colonoscopies every few years for these patients, but this study is investigating whether the blood test could be a safer, less invasive alternative.
Repeat colonoscopies are expensive, inconvenient, and can have serious side effects, yet they only prevent a small percentage of colorectal cancers. This study exists to see if a simple blood test could be just as effective at catching cancer early—giving patients a less invasive option while reducing healthcare costs.
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You will be randomly assigned to one of two groups: either you'll have an annual blood test to monitor for cancer, or you'll continue with the traditional repeat colonoscopies at recommended intervals. The study will follow you for 10 years to see which approach catches cancer earlier and works better overall. Researchers will also ask you questions about your diet, exercise habits, and preferences about the two surveillance methods.
AI-generated summary from trial data · Jul 9, 2026 · Not medical advice
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