Plain-English translation of NCT04970888 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether doing brain exercises combined with physical training—like aerobic and resistance exercise—can help improve memory and thinking skills in people with chronic heart failure. About half of heart failure patients experience cognitive problems (trouble with memory and concentration), which can seriously affect quality of life. Researchers want to see if this combined approach works better than exercise alone or standard care.
Many heart failure patients struggle with memory and thinking problems, but there aren't many proven treatments to help. Recent research suggests that combining brain training with physical exercise might boost cognitive function, and this study will be the first to test this combination specifically in heart failure patients.
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You will be randomly assigned to one of three groups: combined brain training plus exercise, exercise alone, or usual medical care (control group). If assigned to one of the active groups, you will attend three training sessions per week for 6 months—either at a research center or at home, whichever you prefer. Sessions involve aerobic exercise (like walking or cycling), resistance training (weights), and cognitive exercises (mental challenges to boost memory and focus). Researchers will measure your thinking and memory skills, as well as blood flow to your brain before, during, and after the program.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
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