Plain-English translation of NCT04973579 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing a new approach for patients who have two serious heart and blood vessel problems at the same time: narrowing of the carotid artery (which carries blood to your brain) and heart disease that needs urgent surgery. Instead of doing two separate operations weeks apart, doctors will perform both procedures simultaneously in one session using a special stent called CGuard to open the carotid artery while also performing the needed heart surgery. The goal is to reduce the risk of stroke and heart complications that can happen when patients have to undergo two separate surgeries.
Patients with both carotid artery narrowing and serious heart disease face a difficult choice: doing the surgeries one at a time increases the risk of stroke or heart attack between procedures. This trial exists to test whether doing both procedures together at once is safer and more effective than the traditional approach of spacing them out.
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If you are enrolled, you will undergo a single combined procedure performed under one anesthesia in a hybrid operating room. Your doctors will place a special stent in your carotid artery to open the narrowed section, with backup heart-lung support (extracorporeal circulation) standing by if needed, immediately followed by your heart surgery—all in one session. After the procedure, you will be followed with routine visits and tests as part of long-term monitoring to ensure both procedures are healing well and to watch for any complications.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
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