Plain-English translation of NCT04986293 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether using CPAP or BiPAP devices—machines that gently push air into your lungs to help you breathe—can reduce tumor movement during radiation therapy for chest cancers. When you breathe normally, your lungs and tumors move slightly, which can make radiation therapy less accurate. This study will check if these breathing devices can keep your tumor still enough to improve treatment precision.
Tumors in the lungs and chest naturally move when you breathe, which can mean radiation doesn't hit the cancer as effectively as it should. Researchers want to see if this treatment can stabilize your breathing and tumor position, potentially making radiation therapy work better and safer.
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The study happens in two phases. First, about 10 patients will wear CPAP or BiPAP devices briefly to see which setting works best and how it affects breathing patterns. Then, about 21 patients will have weekly CT scan planning sessions—some with and some without the breathing device—to measure how much the tumor moves and whether the device helps reduce movement. Your actual radiation therapy will be given according to standard hospital protocols without the breathing device.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
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