Plain-English translation of NCT04990024 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial compares two different eating plans for people starting semaglutide, a medication for weight loss. Researchers want to see which diet approach—Mediterranean or high-protein/low-carbohydrate—works better when combined with the medication, and how each diet affects the stiffness of your arteries (an important marker of heart health).
We know the medication helps people lose weight, but doctors aren't sure which diet plan works best alongside it or which is better for your cardiovascular health long-term. This study will help answer those questions.
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You'll attend 8 clinic visits over 6 months while taking the medication as your doctor prescribed. You'll be randomly assigned to follow either a Mediterranean diet or a high-protein, low-carbohydrate diet, and a dietitian will teach you about your assigned eating plan at individual sessions. Along the way, you'll answer questions about how well you're sticking to your diet, and the research team will check how your arteries are responding to the treatment.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Lebanon
Sponsor
American University of Beirut Medical Center
Enrollment target
~60 participants
Started
July 2021
Primary completion
September 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 49 Years
Last updated on clinicaltrials.gov in August 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Marlene Chakhtoura, MD, MSc
American University of Beirut Medical Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.