Plain-English translation of NCT04992923 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a long-term observational study of patients with infective endocarditis—a serious infection of the heart's inner lining. Rather than testing a new medication, researchers will carefully track your medical information, test results, and imaging scans from the time of your diagnosis through up to 10 years of follow-up. The goal is to better understand this condition and improve how doctors care for patients like you.
Infective endocarditis is a complex disease that affects each patient differently. By collecting detailed information from a large group of patients over many years, doctors hope to identify patterns that help predict which patients will do well, which ones face higher risks, and which treatments lead to the best outcomes.
You likely qualify if…
You likely don't qualify if…
You will be enrolled at the hospital when you're diagnosed or admitted for treatment of your heart infection. Researchers will collect information about your medical history, symptoms, lab tests, and heart imaging at the time of diagnosis and then during regular follow-up visits over the next 10 years. You won't need to take any new medication or undergo any additional procedures just for the study—doctors will simply gather information that's already part of your routine care.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
France
Enrollment target
~700 participants
Started
September 2020
Primary completion
September 2040
Age range
18 Years and older
Last updated on clinicaltrials.gov in November 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Nadjib Hammoudi, MD, PhD
Pitié-Salpêtrière Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.