Plain-English translation of NCT05007379 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →Researchers are testing a new approach called CAR-macrophages—special immune cells that have been engineered to recognize and attack breast cancer. In this study, doctors will collect a small sample of your tumor during surgery or biopsy (which you're already having as part of your standard care). They'll then grow your cancer cells in the lab and expose them to these modified immune cells to see whether the treatment can effectively fight your cancer.
Current breast cancer treatments don't work the same way for every patient, and some patients develop resistance over time. This research aims to develop a personalized approach using the body's own immune system to target cancer more effectively.
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Your participation is straightforward and fits into your regular cancer care. When you have your planned surgery or biopsy, the medical team will collect an extra small sample of tumor tissue and some blood. These samples go to the laboratory, where researchers will grow your cancer cells and test whether the modified immune cells can attack them. There are no additional visits or treatments required—you're simply donating biological material that would otherwise not be used.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
France
Collaborators
Institut National de la Santé Et de la Recherche Médicale, France
Enrollment target
~100 participants
Started
November 2021
Primary completion
September 2023
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 100 Years
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Nawale HAJJAJI, MD PhD
Centre Oscar Lambret
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.