Plain-English translation of NCT05008276 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Type 2 Diabetes Mellitus research guide →This study is examining how puberty affects the kidneys in teenagers who have obesity, prediabetes, or type 2 diabetes. Researchers believe that during puberty, the kidneys may not get enough oxygen because they're growing rapidly while the body's metabolism is changing. By comparing teenagers with diabetes to healthy peers over two years, the team hopes to understand exactly what happens to kidney function during puberty so they can better prevent kidney disease later in life.
Type 2 diabetes in young people is becoming more common, and kidney damage is a serious complication. However, doctors don't fully understand why some teenagers develop kidney problems during puberty while others don't. This research aims to fill that gap and eventually help prevent kidney disease in young patients.
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You would visit the research clinic at baseline, then again at one year and two years. At each visit, you'll have blood tests, take an oral glucose tolerance test (drinking a sugary drink), and undergo special kidney imaging scans (MRI). Some tests involve injecting safe contrast dyes to measure how well your kidneys filter blood. The visits typically take several hours, but the procedures are not painful—similar to what you'd experience at a regular doctor's appointment.
AI-generated summary from trial data · Aug 3, 2026 · Not medical advice
United States