Plain-English translation of NCT05025774 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is looking at how exercise affects the lungs and heart in young people (ages 8–25) who have survived serious childhood illnesses like leukemia, received a heart transplant, or have chronic lung disease from being born prematurely. Researchers want to understand why some of these survivors may have trouble exercising and what their bodies can safely handle as they grow into adulthood.
Many children with serious chronic illnesses are told they cannot exercise much, either because doctors worry it's unsafe or because the young person feels uncomfortable during activity. This study exists to create better, evidence-based guidelines so that survivors can safely enjoy physical activity and maintain good health as they age into adulthood.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will complete fitness and lung function tests during a visit to the research center. These tests measure how your heart and lungs work during and after exercise, similar to what your doctor might do at a checkup. The study compares results from young people with the three conditions listed above to healthy young people of similar ages, so researchers can understand exercise capacity better and develop safer exercise guidelines.
AI-generated summary from trial data · Jun 8, 2026 · Not medical advice
United States
Sponsor
Masonic Cancer Center, University of Minnesota
Enrollment target
~90 participants
Started
March 2025
Primary completion
November 2026
Age range
8 Years – 25 Years
Last updated on clinicaltrials.gov in November 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Char Napurski, MPH, CCRP
Masonic Children's Hospital, University of Minnesota
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.