Testing a cholesterol medication to prevent liver cancer in advanced liver disease

This trial is testing whether atorvastatin, a medication commonly used to lower cholesterol, might help prevent liver cancer in people with advanced liver scarring. Researchers will compare this medication to a placebo (a dummy pill with no active ingredient) to see if it can reduce the risk of developing hepatocellular carcinoma, the most common type of liver cancer, in people whose livers are already seriously damaged.

People with severe liver scarring (cirrhosis) have a high risk of developing liver cancer, and there are limited ways to prevent it. This trial is exploring whether this medication might offer a new way to protect people with advanced liver disease from cancer development.