Plain-English translation of NCT05029570 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Your heart's natural rhythm has become permanently irregular (atrial fibrillation), which can worsen heart failure. This trial tests whether implanting a special pacemaker and blocking a nerve pathway in your heart can restore a regular rhythm and improve your heart function. The treatment combines atrioventricular node ablation with conduction system pacing — a newer, gentler approach than older pacemaker techniques.
Many people with this combination of conditions don't have proven treatment options that truly improve outcomes. Early observations suggest that regularizing the heartbeat might help, but doctors need to confirm this with a proper clinical trial to make sure it actually works and is safe.
You likely qualify if…
You likely don't qualify if…
If you join the trial, you will be randomly assigned to either receive the pacemaker procedure with heart rhythm ablation, or continue with medication-based heart rate control. You will have regular follow-up visits to check your heart function, symptoms, and overall health. The study will track whether you are hospitalized, how you feel, and whether your condition improves over time.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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