Plain-English translation of NCT05029791 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Melanoma research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is looking at how your immune system and cancer cells change when you receive treatment for advanced melanoma. Researchers will collect small skin samples (biopsies) and blood samples before you start treatment and one month after, to see how your body is responding to the medication your doctors recommend.
Doctors know that some patients respond better to melanoma treatment than others, but they don't fully understand why. By studying these changes in your immune system and cancer cells during this treatment, researchers hope to learn what helps predict who will benefit most from these therapies.
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You will have two skin biopsies taken before you start your melanoma treatment and one blood sample drawn about one month after treatment begins. The study will follow you for up to 5 years, though the most intensive part happens in the first month. Your samples will be stored and analyzed to help researchers understand how your immune system responds to treatment.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
France
Sponsor
Hospices Civils de Lyon
Enrollment target
~100 participants
Started
August 2022
Primary completion
November 2031
Age range
18 Years and older
Last updated on clinicaltrials.gov in December 2023.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Stéphane Dalle, Pr
Hospices Civils de Lyon
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.