Plain-English translation of NCT05039463 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing whether combining platelet-rich plasma (PRP) injections with hyaluronic acid injections works better than hyaluronic acid alone for knee osteoarthritis. PRP is a substance made from your own blood that may help reduce pain and inflammation. The study will track your symptoms and function over one year to see if the combined treatment provides better relief.
Right now, doctors in France aren't sure if PRP injections are truly helpful for knee arthritis because the available research uses very different preparation methods and injection techniques. This study aims to provide clear evidence about whether combining this medication with hyaluronic acid is effective.
You likely qualify if…
You likely don't qualify if…
You will receive either two PRP injections combined with hyaluronic acid, or hyaluronic acid injections alone at Amiens University Hospital. The study will follow you for one year, with researchers checking how your knee pain and function improve over time. You'll likely have follow-up visits to assess your symptoms and complete questionnaires about your recovery.
AI-generated summary from trial data · Jul 20, 2026 · Not medical advice
France
Enrollment target
~100 participants
Started
August 2021
Primary completion
June 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
LAURE LE MONNIER, MD
Centre Hospitalier Universitaire, Amiens
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.