Plain-English translation of NCT05063955 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →This research study is investigating why patients with heart failure often experience muscle loss and weakness — a condition called sarcopenia. Researchers will compare 200 heart failure patients with 50 healthy volunteers, collecting information about muscle health, physical activity, nutrition, and quality of life. The study includes muscle biopsies and blood tests to understand the biological mechanisms behind this muscle loss.
Heart failure patients commonly lose muscle mass and strength, which worsens their overall health and quality of life. However, doctors don't fully understand why this happens or how socioeconomic factors like income and education may play a role. This study aims to fill that gap so better treatments can be developed.
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If you join, you'll visit the study center at baseline to complete physical exams, answer questions about your daily life and nutrition, provide a muscle biopsy sample, and have blood drawn. You'll also be asked about your socioeconomic background and quality of life. Follow-up visits will occur at 12 months and 36 months to track changes in your muscle health and overall condition. Researchers will also check national health registries for any major health events during the study.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
Denmark
Sponsor
Aarhus University Hospital
Enrollment target
~250 participants
Started
December 2020
Primary completion
December 2026
Age range
18 Years – 90 Years
Last updated on clinicaltrials.gov in December 2023.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Henrik Wiggers, Prof.
Aarhus University Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.