Plain-English translation of NCT05081596 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Depression research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a therapy called Problem Adaptation Therapy for Pain (PATH-Pain) — a structured emotional support program — to see if it helps older adults who are experiencing early memory loss, depression, and chronic pain. You would receive either PATH-Pain or standard medical care, and researchers would track how the treatment affects your memory, mood, and daily functioning over one year.
Many older adults struggle with memory loss, depression, and chronic pain at the same time, and these conditions often make each other worse. This trial is testing whether this new treatment could help by teaching people ways to better manage stress and emotions, which might improve both mood and thinking.
You likely qualify if…
You likely don't qualify if…
If you qualify, you'll be randomly assigned to receive either the specialized therapy or standard medical care. The therapy group will have 8 in-person sessions (50 minutes each) at a primary care office over the first 8 weeks, followed by 6 sessions delivered by phone (3 individual and 3 group sessions) over the following months. You'll have check-in assessments at various time points over one year to measure changes in your memory, mood, and how you're doing day-to-day.
AI-generated summary from trial data · Sep 3, 2026 · Not medical advice
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