Recruiting

Better brain imaging to guide electrical tumor treatment placement

Plain-English translation of NCT05086497 on ClinicalTrials.gov ↗ · Source last updated March 2026 · Translation generated August 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing Optune, an electrical therapy treatment for glioblastoma (a serious type of brain cancer). The study compares two ways of planning where to place the treatment patches: the standard method using regular MRI scans, or a newer method using advanced MRI scans that show more detail about where cancer is spreading in the brain.

Doctors want to know if using more detailed brain imaging helps them position the electrical therapy patches in the best possible location, so the treatment can reach more cancer cells and work more effectively.

Do you qualify?

You likely qualify if…

you are at least 22 years old
you have been diagnosed with glioblastoma (confirmed by a biopsy or pathology test)
you have had surgery to remove as much tumor as possible, followed by radiation therapy
you are willing to receive electrical therapy treatment
your blood, liver, and kidney function are adequate for treatment

You likely don't qualify if…

you have cancer in the lower part of your brain (infratentorial tumors)
you are pregnant or may become pregnant
you have active implanted electronic devices like a pacemaker, deep brain stimulator, or spinal cord stimulator
you have a skull defect without a replacement, bullet fragments, or significant bleeding around the tumor
you have an allergy to the conductive gel used to attach the treatment patches

What participation looks like

You will receive Optune as part of your regular cancer care, which involves wearing electrode patches on your scalp that deliver electrical pulses to help fight the cancer. The main difference is that your treatment patches will be positioned using either standard brain imaging or advanced brain imaging techniques. You'll be monitored during the study to see how well the treatment works and how it affects your quality of life.

AI-generated summary from trial data · Aug 5, 2026 · Not medical advice

Better brain imaging to guide electrical tumor treatment placement

What is this trial?

Do you qualify?

What participation looks like

Trial locations