Comparing two forms of an anti-rejection drug after liver transplant

After a liver transplant, your body needs medication to prevent it from rejecting the new organ. This trial compares two different forms of tacrolimus, an anti-rejection drug that prevents your immune system from attacking your transplanted liver. The newer form is taken once daily, while the standard form is taken twice daily. The trial wants to see if the once-daily version causes fewer tremors (shaking) and other side effects in the first few weeks after transplant.

Tremors and shaking are common side effects in the weeks right after liver transplant while patients are adjusting to anti-rejection medications. The once-daily form of this medication has shown promise in other transplant patients for causing fewer of these shaking episodes, and doctors want to find out if it works the same way in liver transplant recipients.