Plain-English translation of NCT05090267 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing two treatments that work through the gut-brain connection: a portable device called transcutaneous vagal nerve stimulation (tVNS) that gently stimulates a nerve in your neck, and a probiotic supplement called Visbiome designed to restore healthy gut bacteria. Researchers think these treatments might reduce inflammation in your body and improve thinking and memory in people living with HIV who also drink alcohol.
People with HIV who drink alcohol often experience problems with thinking and memory, and also have changes in their gut bacteria and increased inflammation. This trial is exploring whether treatments that target the gut-brain connection could help address both of these issues.
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You would receive a portable nerve stimulation device to wear and use regularly, along with the probiotic supplement to take by mouth. The study involves multiple visits where researchers will assess your thinking, take blood samples, and monitor how you're doing. The exact duration and visit schedule would be discussed with the research team, but this is a structured study designed to track changes over time.
AI-generated summary from trial data · Jul 16, 2026 · Not medical advice
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