Plain-English translation of NCT05103683 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This is one of the first times this treatment has been tested in people.
This is a first-in-human study testing a new cancer medication called in patients with advanced solid tumors. Researchers will evaluate how safe the medication is, how well patients tolerate it, and whether it helps shrink tumors. This early-stage study will help doctors understand the right dose and whether this treatment shows promise for future use.
Many patients with advanced cancers need new treatment options because existing therapies don't work well enough or stop working over time. This medication represents a new approach that researchers believe may help, but it has never been tested in humans before, so this study is needed to determine if it is safe and beneficial.
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You would take the medication by mouth (or through another method to be determined) as part of a structured treatment schedule. The study has two phases: first, researchers will gradually increase doses in small groups of patients to find the safest dose, and then additional patients will receive that dose to confirm it works. You will have regular visits for blood tests, imaging scans, and check-ups to monitor your health and how well the medication is working.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
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