Plain-English translation of NCT05106608 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing photobiomodulation therapy — a treatment using a special laser light — to help people with head and neck cancer who suffer from severe dry mouth after radiation treatment. Researchers want to find the best dose of this light therapy and see if it provides lasting relief. You would be in one of three groups: two receiving different strengths of the light therapy, or a placebo control group.
Severe dry mouth is a common and frustrating side effect of radiation therapy for head and neck cancer, and it can last for years. There is no clear agreement yet on the best way to use this light therapy to safely and effectively treat this problem, or whether the benefits last over time.
You likely qualify if…
You likely don't qualify if…
You would attend multiple sessions where you receive light therapy treatments to your salivary glands, wearing protective glasses during each session. One group receives a higher dose of light energy, another receives a lower dose, and the control group receives a sham treatment (the device is off but sounds real). You would use a mobile app to track your dry mouth symptoms and quality of life throughout the study and follow-up period to see if the effects last.
AI-generated summary from trial data · Jun 30, 2026 · Not medical advice
Spain
Sponsor
Universidad de Granada
Enrollment target
~60 participants
Started
July 2022
Primary completion
July 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in January 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Noelia Galiano-Castillo, PhD
Universidad de Granada
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.