Plain-English translation of NCT05107908 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
This study doesn't follow the usual testing phases โ it may be an observational study or a different type of research.
This study is testing whether short, simple brain-training exercises can help people with overweight or obesity eat better by changing how their brain responds to food. Researchers will compare three different approaches: one that pairs food images with positive or negative feelings, one that uses neutral images as a control, and one where you interact with food without eating it. The goal is to understand which method works best at changing eating behaviors and body weight.
Most weight-loss programs focus on willpower or strict diets, but they don't always work because our brains automatically react to food in ways we can't easily control. This study explores whether we can retrain those automatic brain responses to help people naturally make healthier choices.
You likely qualify ifโฆ
You likely don't qualify ifโฆ
You would visit the research center once a week for 12 weeks. Depending on which group you're assigned to, you'll either view food images paired with emotional cues for about 10 minutes, view food images with neutral backgrounds, or spend 10โ30 minutes smelling, touching, and imagining eating real foods (without actually eating them). The researchers will also use brain imaging scans to see how your brain responds to food before and after the training.
AI-generated summary from trial data ยท Jun 2, 2026 ยท Not medical advice
United States
Sponsor
University of Colorado, Denver
Collaborators
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Enrollment target
~228 participants
Started
November 2021
Primary completion
August 2026
Age range
18 Years โ 65 Years
Last updated on clinicaltrials.gov in February 2026.
Reach out to the team running this trial. Response times vary โ some teams are faster than others.
Central contact
Christina Erpelding, BS
University of Colorado, Denver
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first โ no email needed to get started.