Plain-English translation of NCT05112237 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is collecting information from children and young adults (under 18 years old) who have a heart condition caused by changes in the MYBPC3 gene. Researchers want to understand how this genetic heart disease develops, what symptoms and challenges patients face, and how it affects quality of life. By gathering this information from both past medical records and ongoing follow-up, scientists hope to learn more about the natural course of this condition to help improve care in the future.
Right now, doctors don't have a complete picture of how MYBPC3-related heart disease progresses in children or what factors make it more or less serious. This study exists to fill that gap by collecting detailed information that can help doctors better predict outcomes, identify which patients are at highest risk, and eventually develop better treatments.
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If you join the retrospective part, researchers will review your existing medical records to understand your health history. If you join the prospective part (5-year follow-up), you'll be monitored over time, but no extra doctor visits are required—assessments happen during your regular appointments. You'll complete a brief annual blood draw and answer a quality-of-life questionnaire once a year. All other evaluations are non-invasive and fit into your normal care routine.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
United States