Plain-English translation of NCT05120492 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether having weight loss surgery (called sleeve gastrectomy) before a knee replacement leads to better outcomes than having counseling alone before the same surgery. The trial will follow two groups of people with severe knee arthritis and obesity over 9 to 13 months, comparing their recovery and results after knee replacement.
Severe knee arthritis is very painful and often requires knee replacement surgery, but excess weight can make surgery riskier and recovery harder. This trial wants to know if helping people lose weight through surgery before their knee replacement might improve their outcomes and reduce complications.
You likely qualify if…
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If you join this trial, you will be randomly assigned to one of two groups. One group will receive dietary and lifestyle counseling for 9 to 13 months and then have knee replacement surgery. The other group will have weight loss surgery first, along with the same counseling, and then have knee replacement surgery after 9 to 13 months. You will be monitored throughout this time to see how you recover and how well your knee functions.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
Canada
Sponsor
Nova Scotia Health Authority
Enrollment target
~20 participants
Started
April 2022
Primary completion
July 2027
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in August 2024.
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