Plain-English translation of NCT05121779 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
Researchers are comparing two different imaging scans — one called -04 and another called PET-CT — to see which one is better at detecting lung fibrosis and measuring how severe it is. Both scans use a tracer (a harmless radioactive substance) to help doctors see what's happening in your lungs. This study will help determine if the new -04 scan is more helpful than the standard scan currently used.
Lung fibrosis is a serious disease where healthy lung tissue gets replaced by scar tissue, making it harder to breathe. Doctors need the best imaging tools to detect this disease early and track how treatments are working. This study will help doctors decide which imaging method gives them the clearest picture of what's happening in patients' lungs.
You likely qualify if…
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If you enroll, you will undergo two imaging scans on the same day or shortly apart — both are PET-CT scans that involve receiving an injection of a harmless tracer and then lying still while the scanner takes pictures of your lungs. Each scan takes about 30 minutes. The scans are painless and non-invasive, similar to other medical imaging you may have had before.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
China
Safety & dosing
Sponsor
Peking Union Medical College Hospital
Enrollment target
~80 participants
Started
November 2021
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in November 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Zhaohui Zhu, MD
Peking Union Medical College Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.