Plain-English translation of NCT05123482 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This is one of the first times this treatment has been tested in people.
The BLUESTAR trial is testing a new experimental cancer drug called in people with advanced solid tumors that have spread or come back after previous treatment. Researchers want to find the right dose and understand how well this medication works, both when used alone and when combined with other cancer-fighting drugs. This study will help determine if this new treatment might become an option for people whose cancer has not responded well to standard therapies.
Many people with advanced cancers eventually stop responding to standard treatments, and doctors need new options to help them. This trial explores whether this medication could offer a new way to fight certain cancers, either by itself or working together with existing cancer drugs to be more effective.
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Depending on which part of the trial you join, you would take the medication by mouth or receive it as an infusion, either alone or combined with one or two other cancer drugs. The study involves multiple visits to the hospital or clinic for check-ups, blood tests, and imaging scans to see how your cancer is responding and to monitor for side effects. The trial is divided into different phases: first, doctors will test increasing doses to find the safest level, and then they will enroll more patients to see if the medication actually shrinks tumors.
AI-generated summary from trial data · Aug 18, 2026 · Not medical advice
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