Plain-English translation of NCT05123482 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This is one of the first times this treatment has been tested in people.
This trial is testing a new medication called to see if it can help people with advanced cancers that have spread or come back. The medication will be tested in different ways: some patients will receive alone, while others will receive it combined with one or two additional cancer drugs. The main goal is to find the right dose that is safe and effective for treating these cancers.
Patients with advanced cancers often have limited treatment options, especially after standard treatments stop working or become too difficult to tolerate. This trial exists to explore whether this medication—alone or paired with other drugs—might offer a new hope for people whose cancers have progressed despite previous treatments.
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You will receive the study medication either by itself or combined with one or two other cancer drugs, depending on which part of the trial you join. The trial has multiple phases: first, researchers will gradually increase doses to find the safest level, then expand to treat more patients at that dose to see how well it works. You will have regular visits to your study site for blood tests, imaging scans, and check-ins to monitor how you are tolerating the medication and how your cancer is responding.
AI-generated summary from trial data · Jul 20, 2026 · Not medical advice
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