Plain-English translation of NCT05125016 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing two experimental medications called and , which work by activating your immune system to fight prostate cancer cells. You may receive one medication alone, or both medications together, depending on which part of the study you join. The main goal is to find the safest and most effective doses, and to see how well this treatment shrinks tumors.
Men with advanced prostate cancer that has stopped responding to standard hormone therapy have limited options. This medication is designed to use the immune system in a new way to target cancer cells, offering hope for patients who have already tried other treatments.
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The trial has two parts: first, researchers will test different doses of the medication alone or in combination to find the safest level; then, more patients will receive the chosen doses to see how well the treatment works. You will receive the medication by infusion (injection into your vein) and have regular clinic visits for blood tests, scans, and check-ups to monitor how you respond and watch for side effects. The exact schedule will depend on which part of the study you join and how your cancer responds.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
United States