Plain-English translation of NCT05125302 on ClinicalTrials.gov ↗ ·
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This study is testing whether , a medication already approved for treating migraines in adults, is safe and works well for children and teenagers. Researchers want to find the right dose of this medication for younger patients and see how well it helps stop migraine attacks when taken at the first sign of a headache.
Migraines are common and cause real suffering in children and teenagers, but we don't have much information yet about whether this particular medication works safely for them. This trial fills that gap by testing the treatment in the age group that needs it.
You likely qualify if…
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You will visit a clinic or hospital about 120 times across the study sites in the United States over up to 6 months. When you have a qualifying migraine, you'll take a tablet of the study medication (or placebo) at home, then return to track your symptoms. You may be able to take a second dose 2 hours later if the headache is still moderate to severe. Throughout the study, you'll have regular check-ups where doctors will do blood tests, ask about side effects, and have you fill out questionnaires about how you're feeling.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
United States