Plain-English translation of NCT05134454 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
After a stroke or mini-stroke, doctors often check your heart rhythm with an ECG (a simple heart monitor). This trial is testing whether using extended heart monitoring — keeping you on a monitor for longer periods — can catch more cases of irregular heartbeat (atrial fibrillation) than standard short-term monitoring. If found early, this heart rhythm problem can be treated to prevent another stroke.
Many stroke survivors have undetected irregular heartbeat that increases their risk of another stroke, but we don't yet have clear evidence about whether longer monitoring periods actually prevent future strokes or save lives compared to standard monitoring.
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You will be randomly assigned to either standard heart monitoring (24–48 hours of continuous monitoring) or extended monitoring (48 hours of continuous monitoring plus at least two 14-day periods of portable heart monitoring). You'll wear small devices that record your heart rhythm, and researchers will follow you to see if either approach helps prevent future strokes or other heart problems. The study involves about 3,300 older adults across multiple centers.
AI-generated summary from trial data · Jul 19, 2026 · Not medical advice
Sweden
Karolinska Institutet
Collaborators
Uppsala University, Örebro University, Sweden
Enrollment target
~3,300 participants
Started
January 2022
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
70 Years and older
Last updated on clinicaltrials.gov in October 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Johan Engdahl, MD, PhD
Karolinska Institutet
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.